Russell 360 Dri Power Shorts, CP-673451 | 99.89%(HPLC) | In Stock | PDGFR inhibitor. CP 673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM, exhibits >450-fold selectivity over other angiogenic receptors. In glioblastoma tumors, .Cell lines: PAEMolecular Weight: 417.5 Rating: 5 · ‎Free delivery over $500 Russel Brand Religion, CP-673451 | PDGFR Inhibitor. CP-673451 is a potent and selective inhibitor of PDGFR with IC50s of 10 and 1 nM for PDGFRα and PDGFRβ, respectively. For research use only. Rating: 5 · ‎12 votes Bloomingdales Rick Owens, CP-673451|PDGFRα/β inhibitor,potent and selective. CP-673451 is an ATP-competitive inhibitor and is investigated to treat for cancer. It is highly selective against PDGFR-α and PDGFR-β over a variety of other . 14525 Champions Dr, CP-673451, a platelet-derived growth-factor receptor .. by Y Xi · 2014 · Cited by 25 — CP-673451 is a potent inhibitor of PDGFR kinase, being more than 450-fold more selective for PDGFRβ versus other receptors.‎Abstract · ‎Introduction · ‎Materials and methods · ‎Results 15802 Champion Forest Dr, Antiangiogenic and Antitumor Activity of a Selective PDGFR .. CP-673,451 is a novel, reversible, ATP-competitive inhibitor of PDGFR. In kinase assays, this compound does not show substantial potency against any other . 2021 Upper Deck Goodwin Champions, CP 673451 Supplier | CAS 343787-29-1 | CP673451. CP 673451 is a potent and selective PDGFR inhibitor (IC50 values are 1 and 10 nM for PDGFR-β and -α respectively). Selective for PDGFR kinase over a range of . Carburetor For Champion Generator, CP 673451 (CAS Number: 343787-29-1). CP-673,451 is a selective inhibitor of the platelet-derived growth factor receptor β (PDGFRβ) kinase with an IC50 value of 1 nM. It also inhibits the PDGFRα . Cari Champion Bikini, PDGF-R inhibition induces glioblastoma cell differentiation .. by R Lane · 2022 · Cited by 7 — Treatment with CP-673451 reduces proliferation and invasiveness of GBM cells and patient-derived GSCs. To further characterise the effect of CP- . Cari Champion In A Bikini, CP-673451 - Inxight Drugs. CP-673,451 is a potent inhibitor of platelet-derived growth factor beta-receptor (PDGFR-beta) kinase- and PDGF-BB-stimulated autophosphorylation of . Champion A Relationship, Probe CP-673451. The published data for CP-673451 indicates that it is a highly potent and selective inhibitor of PDGFR relative to other anti-antiogenic receptors, including . Champion Assessment Pokemon, CP-673451 ≥95% (HPLC). This ItemPZ0335PZ0149assay. ≥95% (HPLC)assay. ≥98% (HPLC)assay. ≥98% (HPLC)color. white to beigecolor. white to beigecolor. white to off‑whitesolubility. DMSO: 2 mg/mL, clearsolubility. DMSO: 20 mg/mL, clearsolubility. DMSO: ≥30.View 4 more rows Cettire Rick Owens, CP 673451 (5993). View and buy high purity CP 673451 from Tocris Bioscience, a Bio-Techne brand. Potent and selective PDGFR inhibitor. Champion Forest Park, Inhibition of PDGFR by CP-673451 induces apoptosis and .. by Y Yang · 2018 · Cited by 14 — CP-673451 suppresses transcriptional Nrf2 expression via inhibiting PI3K/Akt. •. Inhibition of PDGFRβ sensitizes NSCLC cells to cisplatin. Champion Generator Carburetor, CP-673451 | ≥99%(HPLC) | PDGFRα/β inhibitor. Publications Citing Use of Adooq CP-673451. Kaori Aoto, .et al. Complex formation between platelet-derived growth factor receptor β and transforming growth . Rating: 100% · ‎1 review · ‎Free delivery over $500 Champion Generator Replacement Parts, CP-673451 | Ligand page. The IUPHAR/BPS Guide to Pharmacology. CP-673451 ligand page. Champion Green Apartments, Inhibition of PDGFR by CP-673451 induces apoptosis and .. by Y Yang · 2018 · Cited by 14 — In this study, we investigated the anticancer activity of CP-673451, a potent and selective inhibitor of PDGFRβ, on NSCLC cell lines (A549 and . Champion Insurance Agency, CP 673451 | CAS 343787-29-1 | Cayman Chemical. In several in vivo tumor models, CP-673,451 has antiangiogenic and antitumor activity.Formal Name: 1-[2-[5-(2-methoxyethoxy)-1H-benzimidazol-1-yl]-8-quinolinyl .€57.00 · ‎In stock Champion Printing, PDGFR kinase inhibitor protects against septi. Sep 15, 2022 — CP-673451 treatment was associated with reduced sepsis-induced lung injury such as infiltration of inflammatory cells and thickened alveolar . Champion Qc12yc, CP-673451 for glioblastoma recurrence. Sep 12, 2022 — CP-673451 is a potent inhibitor of platelet-derived growth factor beta-receptor (PDGFRB) kinase- and PDGF-BB-stimulated autophosphorylation . Cyclops Rick Owens, Cp-673451 supplier | CAS 343787-29-1. view and buy high purity Cp-673451 from AOBIOUS, the leading supplier of life science reagents. Champion Rcj6y, Postnatal Tendon Growth and Remodeling Requires .. PDFOct 25, 2017 — Treatment of tendon fibroblasts with PDGF-BB resulted in phosphorylation of PDGFRα and. PDGFRβ, and the addition of CP-673,451 blocked PDGFR . Champion Reverse Weave Jogger, CP-673451. CP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM.£25 delivery Champion Wheels, EP16.04-004 Impact of Gender on .. by OP Ariznabarreta · 2022 — we included tissue sections from a subcutaneous xenograft model treated with or without the small molecule inhibitor CP-673,451 to block PDGFRb signaling. Doc Rick Owens, CP-673451 | SML3368-10MG | SIGMA ALDRICH | SLS. CP-673451. Code: SML3368-10MG D2-231. ADD.£74.91 Champions Defeated As A Stasis Subclass, TTD | Drug: D05QBZ. DIB019651. Drug Name. CP-673451. Synonyms. CP-673,451. Drug Type. Small molecular drug. Indication, Discovery agent, Investigative, [1]. Structure . Champions Of America, Identification of Highly Potent Protein Kinase C‐Related .. by I Slynko · 2016 · Cited by 15 — . several potent protein kinase C-related kinase 1 (PRK1) inhibitors such as CP-673451 (IC50=11 nm) and GSK-943949A (IC50=40 nm). Dr. Martens Rick Owens, Small-Molecule Inhibitors of the Receptor Tyrosine Kinases. by M Hojjat-Farsangi · 2014 · Cited by 243 — CP-673451 is a highly selective benzimidazole, reversible and ATP-competitive inhibitor of PDGFR. This TKI is 450–5000-fold more selective for PDGFRβ . Champions Pool, CP-673451 inhibits the PDGFR-mediated signaling .. Download scientific diagram | CP-673451 inhibits the PDGFR-mediated signaling pathway in non-small-cell lung cancer cells. Note: A549 cells were treated . Clay Champion Mtg, PDGFR-β As a New Therapeutic Target in T-Cell Acute .. Nov 15, 2022 — Mechanistically, CP-673451 inhibits autophosphorylation of dimeric PDGFR-β and in this way prevents phosphorylation of downstream PI3K/AKT, GSK- . Club Champion Bellevue, Thermo Scientific™ CP-673451, 95% 100 mg Products. Fisher Scientific - CP-673451, 95%, ACROS Organics™ Shop Thermo Scientific™ CP-673451, 95% at Fishersci.fi.€580.80 Club Champion Grand Rapids, Platelet Derived Growth Factors PDGFR Inhibitors Clinical .. May 20, 2022 — . Seralutinib, ARRY-768, CP-673451, and MTLH001. Apart from cancer, several ongoing clinical trials are also evaluating the role of novel . Drk Studio Rick Owens, 4QMQ: MST3 in complex with CP-673451. Jul 1, 2015 — MST3 in complex with CP-673451 . This is version 1.2 of the entry. See complete history. Literature. Download Primary Citation. Corruption Of Champions Tips, CP-673451 inhibits the formation of neutrophil .. PDFby G Varghese · 2017 — 3.12 CP-673451 does not induce apoptosis or necrosis in neutrophils . . 4.1 CP-673451 induces neutrophil activation and inhibits an unknown pathway of. Discover Champion, Selleck Chemical LLC CP-673451 5mg 343787-29-1, .. CP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, has .$206.04 · ‎30-day returns Leather Rick Owens Ramones, 4qmq - MST3 in complex with CP-673451 - Summary. MST3 in complex with CP-673451 ; Related, 4QML 4QMM 4QMN 4QMO 4QMP 4QMR 4QMS 4QMT 4QMU 4QMV 4QMW 4QMX 4QMY 4QMZ ; Descriptor, Serine/threonine-protein kinase 24, . Formula Of Champions, CP-673451 | CAS:343787-29-1 - BioCrick. BioCrick is a famous high-purity reference standards manufacturer. Our CP-673451 is confirmed by NMR. Order now can get a discount! Giant Champion Scroll Osrs, Postnatal tendon growth and remodeling require platelet .. by KB Sugg · 2018 · Cited by 21 — CP-673,451 inhibits both PDGFRα and PDGFRβ kinases with greater than 450-fold selectivity compared with other structurally related receptor tyrosine kinases, . Gridiron Champions, CP-673451 | CTD. CP-673,451. Basics; Gene Interactions · Genes · Diseases · Phenotypes · Comps · Pathways · GO · Exposure Studies · Exposure Details · References . Harry Potter Fanfiction Triwizard Champions Protective Of Harry, Medline ® Abstract for Reference 11 of 'Toxicity of molecularly .. Sunitinib-induced pericyte depletion and coronary microvascular dysfunction are recapitulated by CP-673451, a structurally distinct PDGFR inhibitor, . Low Top Rick Owens Big Laces, P317: TARGETING HYPERACTIVE PDGFR-B IN T-ALL .. by S De Coninck · 2022 — Mechanistically, CP-673451 inhibits autophosphorylation of dimeric PDGFR-β and in this way prevents phosphorylation of downstream PI3K/AKT and GSK-3α/β. Kingdom Of Atham: Crown Of The Champions Steam Charts, PDGFRA DepMap Gene Summary. Compound, MOA. AC-710, PDGFR TYROSINE KINASE RECEPTOR INHIBITOR. BMS-536924, IGF-1 INHIBITOR. CEDIRANIB, KIT INHIBITOR, VEGFR INHIBITOR. CP-673451, PDGFR . Master Hong's World Champion Taekwondo, CP 673451 - Cayman Chemical. Product Description: A selective inhibitor of PDGFRβ and PDGFRα kinases (IC50s = 1 and 10 nM, respectively); antiangiogenic and antitumor activity in .£353.00 Nhl Champion Rings, PDGFR kinase inhibitor protects against septic death via .. by Q Wang · 2022 — This suggests that CP-673451 may prevent septic death by inhibiting lymphocyte chemotaxis and alleviating “cytokine storm”. In conclusion, our . Pokémon Fanfiction Ash Champion Level, CP-673451 | PDGFR(α/β) inhibitor | CAS 343787-29-1. CP-673451 (CP673451) is a novel, potent, selective and ATP-competitive inhibitor of PDGFR(α/β) with potential antitumor activity. Purple Champion Shirt, Inhibition of stress fiber formation preserves blood–brain .. by A Manaenko · 2018 · Cited by 37 — CP-673,451 (50mg/kg), p ¼ 0.006). Amelioration of. ICH-induced brain edema was accompanied with improvement of neurological function evaluated 72h after ICH ( . Men Rick Owens Jeans, CP-673451 |CAS:343787-29-1 Probechem Biochemicals. CP-673451 |CP 673451;CP673451 |343787-29-1 |CP-673451 is a potent, selective, orally acitve PDGFR inhibitor with IC50 of 1 and 10 nM for PDGFR-α and PDGFR-β . Stanton Champion, CP 673451 (CP673451) | CAS 343787-29-1. In vivo, CP 673451 inhibits tumor PDGFR-beta phosphorylation, and it also selectively inhibits PDGF-BB-stimulated angiogenesis. CP 673451 causes significant .$150.00 Walk Of Champions, A high-content EMT screen identifies multiple receptor .. by C Lotz-Jenne · 2016 · Cited by 28 — However, CP673451 also reduced ROCK activity in a ROCK cellular assay for . of a selective PDGFR tyrosine kinase inhibitor, CP-673,451. Nike Air Precision 1, CP-673451 - Inhibitor - Crysdot. CP-673451. Catalog No.: CD31002172 CAS No.: 343787-29-1 Purity: 98+%. Acquire COA by email Acquire SDS by email. Pack Size, Price ($), Stock, Quantity . Willow Lake In Champion Ohio, BCL-XL inhibition induces an FGFR4-mediated rescue .. (A-C) Dose-response curve of Co01 treated with a titration of CYC116 (A), CP-673451 (B) and Crenolanib (C) either alone or in combination with 5nM A-1155463 . A Boogie Wit Da Hoodie Last Time Lyrics, CP 673451 - Immuno Diagnostic Oy. · Translate this pageCP 673,451. Awaiting product image. https://www.caymanchem.com/product/19170 · Request offer You see product price after registration. Abc Hoodie, CP-673451 (HY-12050-10mM) at Hölzel-Diagnostika. CP-673451 is a potent and selective inhibitor of PDGFR with IC50s of 10 and 1 nM for PDGFRalpha and PDGFRbeta, respectively. Ahegao Hoodies, CP 673451 - M1941-50mg. Biological Activity. CP 673451 is a pharmacologically selective PDGFR-beta inhibitor and PDGF-BB-stimulated autophosphorylation of PDGFR-beta in cells (IC50 . All Too Well Hoodie, PDGFR. CP 673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM, exhibits >450-fold selectivity over other angiogenic receptors, has antiangiogenic . Pink Rick Owens Low Top, Coronary microvascular pericytes are the cellular target .. Sunitinib-induced pericyte depletion and coronary microvascular dysfunction are recapitulated by CP-673451, a structurally distinct PDGFR inhibitor, . Apex Hoodie, CP-673451 - PDGFR/血小板衍生生长因子受体. · Translate this pageCAS, 343787-29-1. 英文名称, CP-673451. 别名, CS-0207;CP673451. 纯度, Purity≥99%. 分子式, C24H27N5O2. 分子量, 417.5. 外观（性状）, White to off-white Solid. Playboi Carti Rick Owens Boots, CP-673451 [343787-29-1] | HY-12050 | 100 mg. CP 673451 is a selective inhibitor of PDGFRalpha/beta with IC50 of 10 nM/1 nM, exhibits >450-fold selectivity over other angiogenic receptors, has .€1,266.00 Bay Area Hoodie, MST3 in complex with CP-673451 | bioCADDIE Data .. Title: MST3 in complex with CP-673451. Dataset. description: Serine/threonine-protein kinase 24 (E.C.2.7.11.1). privacy: not applicable. aggregation:.CP 673451. CP 673451 - Physico-chemical Properties. Molecular Formula, C24H27N5O2. Molar Mass, 417.5. Density, 1.32. Boling Point, 656.3±65.0 .PKa: 9.84±0.20(Predicted)Molecular Formula: C24H27N5O2CP-673451 Drug Profile. Alternative Names: cp-673451. Latest Update: 2023-03-13 . Product Description. Description of pharmaceutical drug CP-673451 .Regulators of Immune System Function in Autoimmunity and .. Agnieszka Paradowska-Gorycka, ‎Johan Frostegard, ‎Poornima Paramasivan · 2022 · ‎MedicalNHDF were treated with 10 nM of CP-673451 1 hr prior to PDGF-BB (40ng/ml for 48 hrs). Ethanol was used as vehicle control. *P < 0.05, **P < 0.01, .CP-673451 [343787-29-1]. A11350-5 | CP-673451 [343787-29-1]. Antibodies, Recombinant proteins, ELISA kits, RNAi, cDNA clones, Antibody Array, Luminex kits.CP-673451 | CAS 343787-29-1. CP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, .New Clues, Potential Solution to Cancer Drug's Cardiotoxicity. by T Hampton · 2013 — By using the PDGFR inhibitor CP-673451, the researchers were able to recapitulate the kind of cardiotoxicity that sunitinib produces.Pericytes protect rats and mice from sepsis-induced injuries by .. by ZS Zhang · 2023 · Cited by 2 — Pericyte depletion animal model. CP-673451 (S1536, Selleckchem, Houston, TX, USA), a selective PDGFR-β inhibitor, was used to deplete pericytes, .Stromal Signaling in Cancer - Page 124 - Google Books Result. 2022 · ‎MedicalCP-673,451 is another compound which more selectively inhibits PDGFR with low IC50 values (1–10 nM) and exhibits a>450-fold selectivity over VEGFR, .PDGFR kinase inhibitor found to protect against septic .. Sep 15, 2022 — CP-673451 treatment was associated with reduced sepsis-induced lung injury such as infiltration of inflammatory cells and thickened alveolar .Sheet1. XLS11, Tofacitinib citrate (CP-690550 citrate), 2.08742 . 17, Tofacitinib (CP-690550, Tasocitinib), 1.92945 . 98, CP 673451, 1.17898.3066 – TARGETING HYPERACTIVE PLATELET DERIVED .. by S De Coninck · 2022 — Mechanistically, CP-673451 inhibits autophosphorylation of dimeric PDGFR-β and in this way prevents phosphorylation of downstream PI3K/AKT and GSK-3α/β. Both .Proteinkinase Inhibitors - Page 188 - Google Books Result. Stefan Laufer · 2021 · ‎Science. highlighting the most promising derivatives crenolanib (63, CP-868,596) and CP-673,451 (64), with their corresponding inhibitory potencies the .CP-673451. · Translate this pageCP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, .Resistance to Tyrosine Kinase Inhibitors. Daniele Focosi · 2016 · ‎MedicalCP-673451 is an inhibitor of both PDGFRα and PDGFRβ. Different studies have observed that this drug blocked cell growth of mesenchymal-like NSCLC cell line .CP-673451 – 美仑生物. · Translate this pageCP673451；CP-673451 分子式：C24H27N5O2分子量：417.5. 简介：CP-673451 是一种有效的，选择性的血小板源生长因子受体(PDGFR) 抑制剂，抑制PDGFRα 和PDGFRβ 的活性。¥980 to ¥5,970Platelet-derived PDGF promotes the invasion and .. PDFby S Pan · 2020 · Cited by 19 — the PDGFR inhibitor CP-673451 (20 μM) to selectively inhibit PDGF to detect changes in the expression of MMPs when tumour cells.CP-673451,PDGFR抑制剂. · Translate this page货号(SKU)包装规格是否现货价格数量C125124‑1mg1mg现货现价: ¥223.90+‑C125124‑5mg5mg现货原价: ¥823.90+‑C125124‑10mg10mg现货原价: ¥1,483.90+‑View 3 more rowsSelleckChem Kinase Inhibitor Library. PDFCP-724714. Plate 1. B12. Empty. Plate 1. C01. Saracatinib (AZD0530) . CP-673451 . Tofacitinib (CP-690550, Tasocitinib).Product data sheet. MedKoo Cat#: 524866. Name: CP-673451. CAS#: 343787-29-1. Chemical Formula: C24H27N5O2. Exact Mass: 417.21648. Molecular Weight: 417.5. Product supplied as:.PDB 4qmq structure summary ‹ Protein Data Bank in .. Jul 1, 2015 — MST3 in complex with CP-673451 · Function and Biology Details · Structure analysis Details · Ligands and Environments · Experiments and Validation .Coronary microvascular pericytes are the cellular target of .. by V Chintalgattu · 2013 · Cited by 190 — Sunitinib-induced pericyte depletion and coronary microvascular dysfunction are recapitulated by CP-673451, a structurally distinct PDGFR .CP-673451;CAS#343787-29-1;别名;纯度>98%-PF. · Translate this pageCP-673451;CAS#343787-29-1;别名;纯度>98%,MedChem Express (MCE),5mg.Platelet‑derived growth factor‑BB mediates pancreatic .. by T Li · 2021 · Cited by 22 — CP-673451, a potent selective inhibitor of PDGFR tyrosine kinase, was purchased from Selleck Chemicals (cat. no. S1536). Cells were treated with .Small molecules - HMS LINCS Database. HMS LINCS IDNameAlternative NamesLINCS IDPubChem CID10366‑101CP‑673451LSM‑427751015894010367‑101NavitoclaxABT 263; ABT‑263; ABT263LSM‑427762497853810368‑101ASP302625134326View 47 more rowsAkiyama impulsa con sencillo | 25/09/2020 - MLB.com. · Translate this page0:11Tipo de Pitcheo: Slider; Velocidad de Pitcheo: -; Velocidad de Giro: -. Bateo CIN. Akiyama. Z. Velocidad de Salida: -; Ángulo de Partida: .MLB.com · Sep 25, 2020CP-673451 (B2173-5) - 卓昇有限公司. · Translate this pageCP-673451 (B2173-5) ; 庫存單位 B2173-5 ; 分類 ApexBio ; 卓昇有限公司INTERLAB CO.,LTD. 本公司成立於民國八十二年，獨家代理進口歐洲/美國/加拿大等多項抗體試劑及耗材， .The American Shorthorn Herd Book. 1919 · ‎Cattle. red 673449 ( c ) Mollie May , red 673450 ( b ) Red McAdoo , red 673451 ( c ) Florence , r w 673452 ( c ) Red Dorothy . Linnet 173414 C. P. Whitney .SDS of CP 673451, Safety Data Sheets, CAS 343787-29-1. chemBlink provides samples of SDS for CP 673451 (CAS # 343787-29-1). Visit our website today in order to get safety data for more chemicals.Documents of the Senate of the State of New York. New York (State). Legislature. Senate · 1913 · ‎New York (State)The rate for 75 watt , 60 C. P. street , lamps , to New York City , was lowered to . 10.217 12 10,000 00 215,000 GO 40,887 10 68,486 10 6,734 51 1,113 92 .Commercial and Financial Chronicle Bankers Gazette, .. 1885 · ‎Banks and banking1st , cp . , 78 140 1st , reg . , 78 , 1921 * 140 Denv . . 6s , 1910 122 10412 1242 41 40 93 6734 51 90 87 95 82 94 902 76 General mort . , 68 , 1914 .1-[2-[5-(2-Methoxyethoxy)-1H-benzimidazol-1-yl]. Synonyms, 1-[2-[5-(2-Methoxyethoxy)-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine; CP 673451. CAS Number, 343787-29-1. Molecular Formula, C24H27N5O2.The American Short-horn Herd Book: Containing Pedigrees of .. Lewis Falley Allen, ‎William T. Bailey · 1919 · ‎Cattle. red 673449 ( c ) Mollie May , red 673450 ( b ) Red McAdoo , red 673451 ( c ) Florence , r w 673452 ( c ) Red Dorothy . Linnet 173414 C. P. Whitney .Protein Kinase Inhibitors (A-Z) - BioVision. Items 201 - 250 of 870 — CP-466722 · CP-547632 · CP-673451 · CP-690550 · CP-690550 citrate · CP-724714 · CP21R7 · Crenolanib · Crizotinib · CRT0066101 .4qmq - Proteopedia, life in 3D. MST3 in complex with CP-673451. Jmol._Canvas2D (Jmol) "jmolApplet1"[x]. loadScript /wiki/extensions/jsmol/j2s/core/package.js.CP 673 451 - Biochemicals - BioNordika Denmark A/S. CP 673 451. You must be logged in to be able to place orders. Cayman Chemical. CP 673,451 - 10 mg. Model/Product no.: CC-19170-10mg. Add to wish list .Untitled. lq7a6evtoh 8yd673451a 94nuzf7l3o #bxz 3j0s5ftgza y81c3ouhiq sik8rwd243 News . cp 2m0nsbk8d3 Mexborough 1sv34j9zcx #News Mexborough 9l87 fix9b2y1c8